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https://docs.sophos.com/central/Mobile/help/en-us/index.html?contextId=disable-kme-autoenroll

Turn off Knox Mobile Enrollment

To turn off automatic enrollment of Knox Mobile Enrollment enabled devices (“KME devices”) with Sophos Mobile:

  1. On the menu sidebar, click Setup > Google setup, and then click the Samsung KME tab.
  2. Click Revoke KME configuration.

KME devices still connect to Sophos Mobile to enroll, but Sophos Mobile refuses the request.

To completely disconnect Sophos Mobile from Knox Mobile Enrollment, delete the profile for Sophos Mobile in the Samsung Knox Mobile Enrollment console.